Modafinil

Drug Info

• Brand Name: Modafinil;
• Active Ingredient: Modafinil;
• Manufacturer: Teva Pharmaceutical Industries Ltd; Sun Pharmaceutical Industries Ltd; Cipla Limited.

Modafinil pharmacological activity

Modafinil affects the centers of the medulla oblongata and stimulates the vital functions of respiration and blood circulation. According to doctors, the effect of Modafinil is due to the combination of its molecules with the neurotransmitter dopamine.

Dopamine is responsible for many behavioral, emotional and cognitive functions.

The lack of this neurotransmitter is observed in patients with:

• ADHD;
• Social phobias;
• Depression;
• Impaired mental abilities.

Because of the lack of dopamine, it is more difficult for a person to concentrate and perform the tasks set more efficiently.

Modafinil is classified as a nootropic, a drug that enhances specific brain functions. Its task consists in increasing the resistance of brain tissues to increased load and improvement of cognitive functions: memory, speed of thinking and coordination, learning ability. Actually, it is a psychostimulant with a very specific action, which has an obvious advantage over similar drugs in a high degree of pharmacological safety.

Those who have taken Modafinil report that the drug gives them a burst of vigor and energy, even if they have not slept for a long time.

Modafinil has the following therapeutic properties:

• It activates additional dopamine molecules and increases the resistance of the nervous system and brain to loads;
• It improves memory, concentration and attentiveness;
• It increases the speed of psychomotor reactions and muscle tone;
• It increases the speed of memorizing a large amount of information.

It should be noted that for a long time, the nootropics were not perceived by the medical community, and everyone considered the drugs of this group as regular supplements.

Modafinil managed to avoid this only because it was originally marketed as a medicine for drowsiness. For this reason, it has passed more clinical studies than any other nootropic.

Nevertheless, final conclusions on Modafinil have not yet been made, and scientists are studying the phenomenon of its wide therapeutic possibilities.

Indications for use

You can use Modafinil in two ways:

1. As a stimulant of cognitive functions.
2. As a drug for the treatment of neuropsychiatric diseases, namely:

• Attention deficit hyperactivity disorder;
• Multiple sclerosis;
• Bipolar affective disorder;
• Hypersomnia;
• Drug addiction.

In the first case, Modafinil is taken as needed, without reference to a specific treatment regimen.

In the second case, the treatment is usually prescribed by a doctor who identifies the exact regimen and dosage that you should follow to control the symptoms of a disease.

Possible ways of buying cheap Modafinil

First of all, it should be noted that it is not easy to find a reliable Modafinil supplier today. On the Internet, there are many local sellers that operate only in one country and do not supply Modafinil worldwide.

Generally, their prices are higher than those of international suppliers, because they are resellers.

Big online stores offer supply of Modafinil to all countries in the world and lower prices. For this reason, it is much more reliable and advantageous to order Modafinil online in these stores.

It is almost impossible to buy cheap Modafinil in a local drug-store. You will surely need a prescription and, most likely, you will be offered the expensive brand name Provigil. The price of one brand name drug tablet is 5-10 times higher than that of Modafinil Generic. And there is no difference in their therapeutic effect. So, online pharmacies are the only way to buy cheap Modafinil today.

Treatment regimens and dosages

The dosage of Modafinil is determined by the goals of treatment and the diagnosis made by your doctor. It is not recommended to take the drug without first consulting with your doctor. The wrong dosage may result in a large number of adverse effects.

• The standard dose of Modafinil is 200 mg per day.

This dose is prescribed for patients with mild drowsiness, fatigue, weakness, or mild pathologies associated with a lack of dopamine.

This is just the dose that enhances the sensitivity of nerve receptors, improves blood circulation in the brain and improves cognitive functions. For most patients with clinical signs of dopamine deficiency and neuropsychiatric disorders, 200 mg of Modafinil per day is sufficient to improve their health.

• The maximum daily dose of Modafinil is 400 mg.

You can take Modafinil 200 mg tablets at intervals of 10-12 hours and reach the maximum dose of 400 mg per day. This dosage helps to fight drowsiness and provides the maximum stimulation of brain activity. But it is not recommended to use this dosage for more than 3 days in a row.

Recommendations for use

Take the drug in the morning, before breakfast, with a full glass of water. Food slightly reduces the bioavailability of Modafinil, so it would be better to take the medicine at least 30 minutes before a meal.

If you take 2 tablets during the day, the interval between them should be at least 10 hours.

You should not take the drug less than 7-8 hours before going to sleep. Within 8 hours after taking the pill, you will not be able to sleep and will feel a surge of strength and energy. If insomnia manifest during taking Modafinil, you can try to increase the interval between doses and take 1 tablet every 2 days.

When you take Modafinil at a dosage of more than 200 mg per day, you should monitor your own health (to control body temperature, blood pressure, pulse, and brain function). If you feel ill, have a migraine or experience excessive agitation, stop taking the pills.

Missed Dose

If you miss a scheduled intake of Modafinil, do not take 2 or more tablets at once the next time. Wait until the time when you scheduled the next intake of Modafinil and take only 1 tablet. When taking 400 mg or more of Modafinil at a time, overdose symptoms may manifest in patients.

Precautions

Patients are not recommended to take Modafinil:

• Within 6 months after myocardial infarction;
• With left ventricular hypertrophy or mitral valve prolapse;
• With severe heart failure;
• With liver cirrhosis;
• Under 18 years of age;
• During pregnancy;
• With chronic hypertension.

Use of Modafinil during pregnancy

It is contraindicated to take Modafinil during pregnancy. Moreover, it is recommended to plan pregnancy at least 2 months after the end of taking the drug. So, women should use effective methods of contraception.

Possible side effects

Most scientists tend to argue that Modafinil is safer than all known psychostimulants. And incidentally, they are right. Modafinil is non-addictive (when used correctly). When you follow the treatment and dosage regimens, you can avoid severe side effects.

The most likely side effects are as follows:

• Headache of varying intensity (manifest in about 1 of 4 patients);
• Diarrhea;
• Anxiety;
• Dizziness;
• Increased blood pressure.

But allergy is the most dangerous side effect of Modafinil. It mainly manifests in patients with chronic forms of allergies. This drug influences the level of histamine, which is the main mediator of allergies. As a result, when taking the drug, the following reactions are possible: itching, swelling of the extremities, tongue, neck, peeling of the skin, urticaria, and rash.

With these reactions, you should stop taking the drug for some time and consult a doctor.

Modafinil: interaction with other drugs

Since Modafinil affects the level of dopamine and the CNS as a whole, there are a number of drugs and substances that are not recommended to be taken with it, such as:

• Opioids: Methadone, Fentanyl, Hydrocodone, etc.;
• Hormonal contraceptives (it reduces their effectiveness);
• Psychostimulants: Adderall, caffeine, amphetamines, etc.;
• Drugs increasing the level of dopamine.

It is strongly not recommended to take products containing ethanol together with Modafinil. Alcohol increases the load on the CNS and in conditions of increased sensitivity of the nervous system, this can lead to side symptoms.

Storage

Store in a dark place, out of the reach of children, at a temperature not exceeding 25°C.

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You can buy Modafinil online at any time convenient for you. You can always contact us for advice on using Modafinil without a prescription. But we do not make diagnoses online and cannot say for sure what dosage will be safe for you. So, even if you buy Modafinil online without a prescription, we strongly recommend that you consult your doctor.